Bipolar Disorder

Bipolar disorder affects between two and four percent of the population worldwide, yet research has been tragically underfunded relative to other mental health conditions. Bipolar illness is one of the most life-threatening of all serious mental disorders.

Although most sufferers struggle to maintain stable work and social lives, those living with bipolar disorder have paradoxically made outsized contributions to science, academia, government and the arts. Though bipolar disorder is traditionally viewed as a life-long illness, the Baszucki family witnessed first-hand that full recovery is possible using evidence-based metabolic interventions proven to stabilize brain networks.

We partner with principal investigators and their teams, as well as other funders, to advance basic and translational bipolar research. In addition, we invest in individuals, institutions and companies developing precision mental health solutions for bipolar and beyond.

BD²: Breakthrough Discoveries for thriving with Bipolar Disorder

On September 12, 2022, the Baszucki, Dauten, and Brin families joined with the Milken Institute to launch BD²: Breakthrough Discoveries for thriving with Bipolar Disorder. BD² is a global platform coordinating science across disciplines and national borders to tackle this complex and still poorly understood disorder.

Read more
Catalyzing New Research in Bipolar Disorder

In addition to ketogenic metabolic intervention research, we have been supporting cutting-edge research on mood disorders for several years. To accelerate our giving in bipolar disorder, specifically, the Milken Institute assisted us in running a competitive program in 2021 which resulted in 45 research grants to advance bipolar therapeutic discovery and translational research.

Read more

Highlighted Grants

Dr. Hilary Blumberg Yale University A Novel Mitochondrial Target as a Therapeutic Approach to Bipolar Disorder Read more
Dr. Helen J. Burgess University of Michigan Sleep Across the Seasons in Bipolar Disorder: Mood, Sleep, Melatonin and Oxidative Stress Changes with the Lunar Cycle in the Prechter Bipolar Longitudinal Study Read more
Dr. Michael Fox, Dr. Shan Siddiqi and Dr. Joseph Taylor Brigham and Women’s Hospital Identifying Transcranial Magnetic Stimulation Targets for Mood Stabilization in Bipolar Disorder Read more
Dr. David Miklowitz University of California, Los Angeles A Collaborative Treatment Network for Youth With or at High Risk for Bipolar Disorder Read more
Dr. Gregory Fonzo University of Texas | 2020 One Mind Rising Star Award Targeting Neural Structures in the Amygdala to Treat Mood Disorders Read more
Dr. Emily Provost University of Michigan Predicting Individual Outcomes for Rapid Intervention (PRIORI) in Bipolar Disorder, Ambient Emotion Study Read more
Dr. Nolan Williams Stanford University Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) for Treatment-Resistant Bipolar Depression Read more
Dr. Peter Zandi Johns Hopkins University Leveraging a collaborative network to test a novel iTBS treatment for bipolar depression Read more