August 26, 2026—In 2009, medical student Shebani Sethi watched a patient in a weight loss program make a remarkable recovery. The dietary intervention she underwent alleviated her schizophrenia symptoms, something the woman had tried – and failed – to treat with medication for years. That experience sent Shebani down a medical path that would lead her to treating mental health in a radically different way.

Published today in Schizophrenia Bulletin, a first-of-its-kind randomized controlled trial (RCT) from researchers at the University of California, San Francisco (UCSF), and funded in part by the National Institute of Mental Health (NIMH), adds to growing literature on the potential benefit of a ketogenic diet for treating psychotic disorders.